We are the market leaders in automated pKa, logP/D and solubility measurement.

At Sirius Analytical we design and manufacture highly automated instruments to measure physicochemical parameters - pKa, logP & logD, solubility and dissolution. We also operate as a CRO providing a wide range of physical chemistry analytical services.

Products

Sirius Analytical Products

SiriusT3 tech specs

Technical specification

   

pH electrodes

 Ag/AgCI, double junction reference

Stirrer

 Overhead, variable speed, computer controlled

Temperature probe

 Thermocouple, Temperature measured with every datapoint

Precision dispensers

 Water, Acid, base, partition solvent, CoSolvent, six-installed, via automated 6-way valve

MultiTip dispenser

 6 tip capillary bundle

Probe movement

 Fully automated X-Z axis on titrator module

Electrode storage/calibration

 Home position for electrode storage and pH7 buffer positions for calibration

Washes

 Two static washes and flowing water wash station

Autoloader

 Holds up to 192 samples, automatic gripper arm for transfer to sample position

Purge gas

 Two internal flow meters, nitrogen or argon required

Partition solvents

 Supports 7 including octanol, dodecane, toluene

CoSolvents

 Supports 10 including Methanol, Acetonitrile, DMSO and MDM

System standardisation

 Sirius Four-Plus(TM) procedure

pH-range

 1.8 - 12.2

Assay volume

 1mL

Services required

 One mains power inlet (110 or 240 V)

Connection to the PC

 One USB Cable

Computer

 Windows 2000, XP or Vista

Services required

 A computer is required to run the SiriusT3 software that accompanies the instrument. The minimum specification is shown below.

PC specification

 Minimum 1ghz processor, Minimum 1 GB RAM, 500mg free hard disk space, CD ROM/DVD-drive, 1024 x 768 screen display, Graphics card that supports OpenGL, One free USB port.

SiriusT3 connection to the PC

 USB Cable, included

Software required
 

 Windows 2000, XP or Vista
 

Sirius will supply all the necessary cables between the instrumentation and the PC. Access to a colour printer, either local or networked, is recommended