We are the market leaders in automated pKa, logP/D and solubility measurement.

At Sirius Analytical we design and manufacture highly automated instruments to measure physicochemical parameters - pKa, logP & logD, solubility and dissolution. We also operate as a CRO providing a wide range of physical chemistry analytical services.

About Us

Sirius Analytical

  • 2000

    ProfilerSGA for high throughput pKa measurement is launched at LogP2000 in Lausanne, Switzerland. Also on show at the meeting are the PCA200 and the new software suite RefinementPro made its debut. Beta-test version of our prediction software, Absolv is exhibited. Four new products launched in one year! The Third Users' Meeting is held in Lausanne, directly after LogP2000. Record attendance of over 125 delegates.

  • 1999

    First GLpKa sale to India. D-PAS add-on, for UV pKa measurement is launched: 20 sold in first 6 months.

  • 1998

    Expansion continues: new science, engineering and software staff hired. A number of joint research and development programmes underway. The Second Sirius Users' Meeting held in Paris, France.

  • 1997

    GLpKa is launched at Pittcon. Combined sales of PCA101 and GLpKa exceed 100 units. Research into spectrophotometric/pH-metric pKa measurement begins.

  • 1996

    Sirius website opened. GLpH launched. First Sirius Users' Meeting and Second Symposium held in Frankfurt, Germany. First PCA101 sale in Far East to Chungnam University, Korea. STAN Volume 2 published. Contract analysis service begins. Sirius appoint distributor in the US and Canada.

  • 1995

    Sirius wins the 'first-time exporter' category in the UK Exporter of the Year award. pKaLOGP for Windows software released. PCAcheck instrument quality-assurance scheme introduced. First Sirius symposium on Ionisation, Partitioning and Lipophilicity held in London. Sirius moves to larger premises.

  • 1994

    Sirius 'journal' STAN launched to publish the many results obtained in the Sirius lab. Research begins using PCA101 to study liposome/water partitioning. Sirius featured on the front page of Chemistry in Britain.

  • 1993

    Eight pKas measured simultaneously in one sample using PCA101. PDP (partition-derived pKa) method developed. Sirius begins to expand, employing full-time engineering and applications laboratory staff. First PCA101 Users' Training Course held.

  • 1992

    First PCA101 sale in the USA, to Rhone-Poulenc Rorer, PA. pH-metric logP paper 1 published: Difference plots for determining ion-pair octanol-water partition coefficients of multiprotic substances. Sirius moves to larger premises.

  • 1991

    World's first automated titration system dedicated to pKa and logP measurement, the PCA101, is launched by Sirius. First sale to Napp Pharmaceuticals, Cambridge, UK

  • 1990

    Sirius wins UK Government's Small Firms' Merit Award for Research and Technology (SMART award).

  • 1989

    Sirius founded with the goal: to become a world-class manufacturer of innovative instrumentation for chemical analysis. Other names suggested for the company include Proton+, Quadrion, and Iontech. Work begins on development of PCA101.