LogD screening
LogD (at pH7.4) determined using ProfilerLDA. Isocratic liquid-liquid chromatography, samples partitioning into octanol. Sample must contain a UV-active chromophore. LogD range 0 to 5. Samples measured at pH 7.4. Measures ionisable and non-ionisable compounds.
Click here for LogD profiling questionnaire
Sirius appointed as distributors for Kibron Delta-8
24.7.08
Sirius are now the exclusive distributors in UK, USA and Canada for the Kibron Delta-8 system for measurement of surface tension and phospholipidosis.
Cambridge scientists set solubility challenge
11.8.08
A new paper from scientists using Sirius solubility techniques at the University of Cambridge asks "can you predict solubilities of 32 molecules using a database of 100 reliable measurements?".
BPC 2008
09.9.08
John Comer from Sirius is giving a presentation on solubility and supersaturation, and their effects on predicting oral absorption.
AAPS Annual Meeting
16.11.08
Sirius will have a booth at this years AAPS Annual Meeting in Atlanta, Georgia.