GLpH - automated pH measurement

Overview

For accurate and automated measurement of pH in a wide range of samples

  • High degree of accuracy
  • Easy to use
  • Automatic calibration and reminders
  • Available in single or autosampler versions
  • One-button operation for most measurements
  • Built-in GLP
  • 'Normal' and 'Supervisor' access modes

GLpH automates all the actions of pH measurement to create the world's most accurate pH meter. The electrode, stirrer and temperature probe are moved automatically between calibration buffer solutions, three wash solutions and the sample. All the errors associated with manual pH measurement are eliminated. The accuracy and repeatability are outstanding.

Sirius GLpH is used in Quality Control laboratories and process monitoring from petrochemicals to personal care. GLP protocols are built-in. Calibration can be pre-programmed to take place at user-defined intervals, so GLpH is always calibrated and ready to go.

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GLpH video

This video shows a single sample version of GLpH measuring the pH of a sample of Honey. In the video you can see the washing steps that clean the electrode automatically before and after the pH measurement, and you can also see the collection of the pH point by real-time recording of the electrode stability. When dealing with a viscous sample, the instrument waits after exiting the sample to allow drips to fall from the electrode before moving.

Get Flash player to see this video.

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Technical specification

pH electrodes

Ag/AgCI, double junction reference, general purpose (supplied as standard)
Ag/AgCI, double junction reference, green glass (for high pH applications)
Ag/AgCI double junction reference, micro diameter 4.3mm
Ag/AgCI flat end, Teflon junction* (for plates, shallow solution depth)
Ag/AgCI sleeve style Teflon junction* (for high electrode flow rate application)

Electrode fill sol.

Standard Sirius fill solution (*Teflon junctions require gel filling solution)

Electrode storage /calibration

Two positions for each buffer solution, one wash and one calibration

Single sample version

Sample placed in position by hand

Temp. probe

PT100 allows automatic temperature compensation

Probe movement

Fully automated X-Z axis

Resolution of displayed data

0.1, 0.01, 0.001 pH units (selectable)

Calibration

pH7 (or 6.86) buffer, then pH4 and/or pH10 (or 9.18); Buffers traceable to BS, DIN or NIST

Washes

Two water washes and one special wash station provided

Storage position

One (pH7 Buffer solution)

Contamination prevention

Probe assembly never travels over unmeasured samples

Measurement methods

20 available: in automated operation it is possible to interrupt methods to introduce 'rush' samples

Stirrer

Overhead, variable speed

Autosampler version tray

Holds 32 (33mm diameter, plastic) or 50 (25mm glass) sample vials, option to be temperature controlled with external circulating bath.

Keypad

Liquid-crystal 16-line display for text and graphics, 22-buttons for numeric data entry

Keyboard

Mini keyboard for alphanumeric data entry, standard on Autosampler but optional in Single Sample

pH-range

0-14 displayed. Accurate between 1.8 and 12.2

Sample container dimensions

Max height 135mm, minimum diameter 25mm (variable if automation disabled)

Data reported

mV, Temperature, pH by time or stability

Automated

For unattended and overnight operation. Data upload. Maintenance prompts.

Services required

One mains power inlet (110 or 240 V)

Connection to the PC

Cable from GLpH to PC serial comm port

Software

GLpH Firmware Version 2.014

Dimensions of single sample

W570 x D510 x H470mm

Weight

18kg

Dimensions of packaging

W660 x D510 x H320mm

Weight of packed

21kg

Dimensions of Autosampler

W610 x D500 x H570mm

Weight of Auto/s

22kg

Dimensions of packaging

W710 x D600 x H280mm (for the autosample base only)

Weight of packed

25kg (for the autosampler only)

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Literature

Electronic copies of our GLpH brochure and technical specifications are available for download:

> GLpH Brochure
> GLpH Technical Specifications
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New SiriusT3 Instrument launched

25.03.09

Sirius Analytical launch new SiriusT3 instrument for fully automated ionisation (pKa), lipophilicity (logP, logD) and solubility measurement.

Read more

Fast Solubility measurements using the Delta-8

16.12.08

A new paper from scientists using the Delta-8 surface activity profiling system demostrates the use of the system to measure solubility in a 96 well plate format.

Read more

SMi ADMET Workshop

30.06.09

Sirius are running the pre-conference workshop entitled "Supersaturation and Solubility in Formulation Excipients: Promoting a Compounds BCS Class".

Read more

IAPC Physico-Chemical Methods Conference - Croatia

27.09.09

Sirius will be speaking and exhibiting at the 1st World Conference on Physico-Chemical Methods in Drug Discovery and Development.

Read more

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