RefinementPro2 - software for GLpKa & PCA200

RefinementPro2

Overview

Latest software for assay setup, instrument control and data processing for pKa, logP, logD, solubility and dissolution experiments on GLpKa, D-PAS and PCA200

Why Upgrade to RefinementPro2?

  • Automatic refinement of pH-metric and D-PAS data - saves valuable time
  • Automatic import of calibration data
  • Automatic Turbidity sensing with D-PAS probe
  • Assay planner - automatically create optimized assays from basic compound info
  • Automatic clipping of data
  • Automatic selection of reference ranges for D-PAS assay
  • Dataset quality marker
  • Improved 'Approx' function with Auto-Bjerrum analysis

RefinementPro 2 software controls GLpKa, PCA200 and D-PAS instruments and calculates pKa and logP results from the experimental data. RefinementPro 2 improves and enhances the ground-breaking technology introduced in RefinementPro 1, and its exciting new features enable increased work efficiency.

Among these new features, a D-PAS probe can be used to detect turbidity during a titration. This feature can be requested when setting up an pH-Metric titration for pKa, with or without cosolvents present. It will also indicate turbidity during any D-PAS titration for pKa. The D-PAS turbidity option is used for titrations in the standard Sirius vials.

The Assay Planner feature allows users to set-up a tray of assays from a simple text file without manually setting up the tray sample-by-sample. It's a great time saver for analysing substantial numbers of sample using similar methods.

A standard RefinementPro 2 installation can be enhanced by adding Fast D-PAS software for four minute pKa measurement, and CheqSol software for solubility measurement.

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Screenshots

Control Refine
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Collect Turbidity
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New Scientific Paper Published

07.12.09

New paper from Sirius explains how our solubility measurements work, and introduces new methods for evaluating supersaturation.

Read more

New Scientific Paper Published

01.07.10

New paper - Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship.

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ACS Fall 2010 National Meeting, Boston

22.08.10

Sirius will exhibit at this meeting.

Read more

Physchem Forum 9, Barcelona

17.09.10

Sirius will exhibit at and sponsor the next Physchem Forum meeting in Barcelona

Read more

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